The pharmacokinetics of oxycodone after intravenous injection in adults.
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چکیده
منابع مشابه
Pharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
Six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. Blood samples were collected before and at various time intervals after the administration of the drug. Serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. Non...
متن کاملpharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. blood samples were collected before and at various time intervals after the administration of the drug. serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. non...
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AIM To study the dose effects on pharmacokinetics of m-Nif. METHODS Fifteen rabbits were divided into 3 groups receiving i.v. m-Nif 0.5, 1, and 2 mg.kg-1. Plasma levels of m-Nif were determined with HPLC method. RESULTS The concentration-time data were fitted with 2-compartment model. After i.v. 1 mg.kg-1, the parameters were: Vd = 0.37 +/- 0.10 L.kg-1, T1/2 alpha = 6.4 +/- 2.9 min, T1/2 be...
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1. Oxycodone hydrochloride (0.1 mg kg-1) was given by intravenous bolus to 18 children after ophthalmic surgery. Plasma was sampled for up to 8 h. Blood pressure, heart rate, peripheral arteriolar oxygen saturation, end-tidal carbon dioxide and halothane concentrations and ventilatory rate were also recorded. 2. Mean (+/- s.d.) values of drug clearance and volume of distribution (Vss) were 15.2...
متن کاملPharmacokinetics of GdDTPA/dimeglumine after intravenous injection into healthy volunteers.
Pharmacokinetic studies of GdDTPA/dimeglumine in man show a rapid renal clearance and no evidence for dissociation or retention of the complex in the body. These features, in conjunction with its strong proton relaxation enhancement and its low toxicity suggest that this complex may be an excellent contrast medium for magnetic resonance imaging.
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1991
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1991.tb03942.x